t(4;22)(q12;q11)

Preferred Label : t(4;22)(q12;q11);

NCIt synonyms : t 4 22 q12 q11;

NCIt definition : A chromosomal translocation involving breakpoints within the q12 band on the long arm of chromosome 4 and the q11 band on the long arm of chromosome 22. This rearrangement is associated with BCR-PDGFRA fusion gene expression and Philadelphia-chromosome negative myeloid leukemia.;

Details

Origin ID

C37882;

UMLS CUI

C1515770;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
cytogenetic_abnormality_involves_chromosome
- Human Chromosome 22 [NCIt concept]
- Human Chromosome 4 [NCIt concept]
is_abnormality_of_gene
- BCR/PDGFRA Fusion Gene [NCIt concept]
molecular_abnormality_involves_gene
- BCR Gene [NCIt concept]
- BCR/PDGFRA Fusion Gene [NCIt concept]
- PDGFRA Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients