Pancreatic Neuroendocrine Carcinoma

Preferred Label : Pancreatic Neuroendocrine Carcinoma;

NCIt synonyms : Pancreatic NEC; High-Grade Pancreatic Neuroendocrine Carcinoma; High Grade Pancreatic Neuroendocrine Carcinoma; Pancreatic Endocrine Carcinoma; Poorly Differentiated Pancreatic Endocrine Carcinoma; PanNEC; Poorly Differentiated Neuroendocrine Neoplasm;

NCIt related terms : Malignant Pancreatic Endocrine Tumor; Islet Cell Cancer; pancreatic endocrine cancer; Malignant Islet Cell Tumor; CARCINOMA, ISLET CELL, MALIGNANT; Islet cell carcinoma; Pancreatic Neuroendocrine Cancer;

NCIt definition : An aggressive high-grade carcinoma with neuroendocrine differentiation that arises from the islet cells of the pancreas. It is composed of malignant small or large cells. The mitotic count is more than 20 per 2 mm2 and/or the Ki-67 index is more than 20%.;

Alternative definition : NCI-GLOSS: Cancer arising from cells in the islets of Langerhans, which are found in the pancreas.; CDISC: A malignant endocrine neoplasm arising from islets of Langerhans of the pancreas.;

Neoplastic status : Malignant;

ICD-O code : 8150/3;

Codes from synonyms : CDR0000530385; CDR0000046343;

Details

Origin ID

C3770;

UMLS CUI

C1328479;

Automatic exact mappings (from CISMeF team)
- Islet cell adenocarcinoma [ICD-11 Extension code]
- Islet cell carcinoma [ICD-9 code]
- Neuroendocrine carcinoma of pancreas [ORDO Disease]
- Neuroendocrine neoplasms of pancreas [ICD-11 Subcategory]
- islet cell tumor [DO Concept]
- pancreatic cancer [MedlinePlus Topic]
- pancreatic endocrine carcinoma [DO Concept]
Currated CISMeF NLP mapping
- Carcinoma of endocrine pancreas (disorder) [SNOMED CT concept]
- Islet cell carcinoma [ICD-O code]
- Islet cell carcinoma (morphologic abnormality) [SNOMED CT concept]
- Malignant tumor of Islets of Langerhans (disorder) [SNOMED CT concept]
- carcinoma, islet cell [MeSH Descriptor]
- carcinoma, islet cell [MeSH concept]
- islet cell carcinoma [Disease (Nov.)]
- islet cell carcinoma [SNOMED Notion]
DO Cross reference
- pancreatic endocrine carcinoma [DO Concept]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Excludes anatomical site(s)
- Exocrine Pancreas [NCIt concept]
- Head and Neck [NCIt concept]
- Lung [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Pancreas [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Carcinoma of endocrine pancreas (disorder) [SNOMED CT concept]
- Islet cell carcinoma [ICD-O code]
- Islet cell carcinoma (morphologic abnormality) [SNOMED CT concept]
- Malignant neoplasm of islets of Langerhans [MedDRA Preferred Term]
- Malignant neoplasm of islets of langerhans [ICD-9 code]
- Malignant pancreatic islet neoplasm [MedDRA LLT]
- Malignant tumor of Islets of Langerhans (disorder) [SNOMED CT concept]
- Pancreatic islet cell carcinoma [MedDRA LLT]
- Pancreatic islet cell neoplasm malignant NOS [MedDRA LLT]
- carcinoma, islet cell [MeSH concept]
- carcinoma, islet cell [MeSH Descriptor]
- islet cell carcinoma [Disease (Nov.)]
- islet cell carcinoma [SNOMED Notion]
- malignant neoplasm of islets of langerhans [SNOMED Notion]
- pancreatic endocrine carcinoma [DO Concept]
concept_is_in_subset
- CDISC SEND Terminology [NCIt concept]
- CDISC SEND Tumor Findings Results Terminology [NCIt concept]
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Lesion [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Well Differentiated Lesion [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Lesion [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell of the Digestive System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Islet Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Islet of Langerhans [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Islet of Langerhans [NCIt concept]
- Pancreas [NCIt concept]
- Pancreatobiliary System [NCIt concept]

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