NY-ESO-1 Protein Vaccine Plus Montanide ISA-51 VG - CISMeF
NY-ESO-1 Protein Vaccine Plus Montanide ISA-51 VGNCIt concept
Preferred Label : NY-ESO-1 Protein Vaccine Plus Montanide ISA-51 VG;
Obsolete resource : true;
NCIt synonyms : NY-ESO-1 Protein Vaccine Emulsified In Montanide ISA-51 VG; Montanide-ISA-51 NY-ESO-1-Peptide-Vaccine;
NCIt definition : A cancer vaccine consisting of an immunogenic peptide derived from the cancer-testis
antigen (NY-ESO-1) and emulsified in the immunoadjuvant Montanide ISA-51 VG, with
potential immunomodulating and antineoplastic activities. Upon subcutaneous vaccination,
the NY-ESO-1 protein vaccine emulsified in Montanide ISA-51 VG may stimulate the host
immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against
tumor cells expressing the NY-ESO-1 antigen, resulting in tumor cell lysis. NY-ESO-1,
an antigen found in normal testes and various tumors, including bladder, breast, hepatocellular,
melanoma, and prostate cancers. The surfactant mannide monooleate in Montanide ISA
51 VG is derived from vegetable-grade (VG) oleic acid that was purified from olive
oil.;