Preferred Label : NA17-A Antigen;
NCIt synonyms : NA17-A;
NCIt definition : A specific melanoma antigen protein derived from a patient (NA17) with cutaneous melanoma
metastases. When administered in a vaccine formulation, NA17-A antigen may stimulate
a cytotoxic T lymphocyte (CTL) response against tumors that express this antigen,
which may result in a reduction in tumor size. The NA17-A antigen is part of the enzyme
N-acetyl glucosaminyltransferase V (GnT-V). Approximately half of melanomas have been
found to express significant levels of this atypical protein, which is not expressed
by normal tissues.;
Origin ID : C37450;
UMLS CUI : C1134655;
Semantic type(s)
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
