Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858

Preferred Label : Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858;

NCIt synonyms : Autologous Heat-Shock Protein 70 Peptide Vaccine;

NCIt definition : A recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models. (NCI04);

Molecule name : AG-858;

Details

Origin ID

C37448;

UMLS CUI

C1328058;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- AG-858/Imatinib Mesylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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