Preferred Label : Anaplastic Large Cell Lymphoma;
NCIt synonyms : Ki-1 Anaplastic Large Cell Lymphoma; Ki-1 ALCL; CD30 Positive Anaplastic Large Cell Lymphoma; ALCL; Ki-1 Lymphoma; Anaplastic Large Cell Lymphoma, T Cell and Null Cell Type;
NCIt related terms : Anaplastic large cell lymphoma, NOS; NHL, anaplastic large cell lymphoma; Anaplastic large cell lymphoma, CD30 ;
NCIt definition : A peripheral (mature) T-cell lymphoma, consisting of usually large anaplastic, CD30
positive cells. The majority of cases are positive for the anaplastic large cell lymphoma
(ALK) protein. The most frequently seen genetic alteration is a t(2;5) translocation.
Majority of patients present with advanced disease. The most important prognostic
indicator is ALK positivity, which has been associated with a favorable prognosis.
(WHO, 2001);
Alternative definition : NCI-GLOSS: An aggressive (fast-growing) type of non-Hodgkin lymphoma that is usually
of the T-cell type. The cancer cells express a marker called CD30 or Ki-1 on the surface,
and may appear in the lymph nodes, skin, bones, soft tissues, lungs, or liver.;
Neoplastic status : Malignant;
ICD-O code : 9714/3;
Codes from synonyms : CDR0000575433; CDR0000045552;
Origin ID : C3720;
UMLS CUI : C0206180;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Disease excludes abnormal cell
- Disease excludes normal cell origin
- Has associated anatomic sites
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_may_have_molecular_abnormality
- human_disease_maps_to_eo_disease
