Preferred Label : Digestive System Adenoma;
NCIt synonyms : GI System Adenoma; Gastrointestinal Adenoma; Gastrointestinal System Adenoma;
NCIt definition : A sporadic or less frequently familial neoplasm that arises from the glandular epithelium
of the gastrointestinal tract and liver. In the gastrointestinal tract, it manifests
as a polypoid or flat circumscribed lesion. Morphologically, it is characterized by
a proliferation of neoplastic glandular cells and is associated with dysplasia. Based
on the growth pattern, it may be classified as tubular, villous, or tubulovillous.
The dysplasia is classified as mild, moderate, or severe. The frequency of malignant
transformation depends on the size of the lesion and the degree of dysplasia. Larger
gastrointestinal tract adenomas with severe dysplastic changes carry a higher risk
of progression to invasive adenocarcinoma. Gastrointestinal tract adenomas may present
as solitary or multifocal lesions. In the liver, it arises from the hepatocytes. Grossly,
it appears as a soft, round mass. Morphologically, the neoplastic cells resemble normal
hepatocytes.;
Neoplastic status : Undetermined;
Origin ID : C36207;
UMLS CUI : C0948101;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- DO Cross reference
- Disease excludes abnormal cell
- Has associated anatomic sites
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_associated_disease
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
