" /> Acute Promyelocytic Leukemia with a Variant RARA Rearrangement - CISMeF





Preferred Label : Acute Promyelocytic Leukemia with a Variant RARA Rearrangement;

NCIt synonyms : Acute Promyelocytic Leukemia with Variant Translocations; Acute Promyelocytic Leukemia with Other RARA Rearrangements; Acute Myeloid Leukemia with a Variant RARA Rearrangement;

NCIt related terms : AML with Variant RARA Translocation; Acute Myeloid Leukemia with a Variant RARA Translocation;

NCIt definition : A term that refers to acute promyelocytic leukemias that show variant translocations involving the RARA gene. The variant fusion partners include NUMA1, ZBTB16, STAT5B, and NPM1.;

Alternative definition : NICHD: A term referring to acute myeloid leukemias which show variant translocations involving the RARA gene. The variant fusion partners include NUMA1, ZBTB16 (PLZF), STAT5B, and NPM1. These leukemias often have the morphologic features of acute promyelocytic leukemia.;

Neoplastic status : Malignant;

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10/07/2025


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