Intrahepatic Cholangiocarcinoma

Preferred Label : Intrahepatic Cholangiocarcinoma;

NCIt synonyms : Intrahepatic Bile Duct Carcinoma; iCCA; Intrahepatic Cholangiocellular Carcinoma; iCC;

NCIt related terms : CHOLANGIOCARCINOMA, INTRAHEPATIC, MALIGNANT; Intrahepatic Carcinoma of Bile Duct; Intrahepatic Bile Duct Cancer (Cholangiocarcinoma); Intrahepatic Carcinoma of the Bile Duct;

CISMeF acronym : ICC;

NCIt definition : A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.;

Alternative definition : CDISC: A malignant neoplasm of the liver arising from/comprising cells resembling those of bile ducts.;

Neoplastic status : Malignant;

Codes from synonyms : C22.1;

Details

Origin ID

C35417;

UMLS CUI

C0345905;

Automatic exact mappings (from CISMeF team)
- Cirrhosis, familial [OMIM Phenotype]
- Convulsions, familial infantile, with paroxysmal choreoathetosis [OMIM Phenotype]
- Insertion of pleural tube drain (procedure) [SNOMED CT concept]
- Malignant neoplasm of intrahepatic bile ducts [ICD-11 Subcategory]
- Primary cholangiocarcinoma of intrahepatic biliary tract (disorder) [SNOMED CT concept]
- calcium channel blockers [MeSH Descriptor]
- congestive heart failure [MeSH concept]
- heart failure [MeSH Descriptor]
Currated CISMeF NLP mapping
- Cholangiocarcinoma [MedDRA Preferred Term]
- Cholangiocarcinoma [ORDO Disease]
- Cholangiocarcinoma [ICD-9 code]
- Cholangiocarcinoma [PASCAL descriptor]
- Cholangiocarcinoma [ICD-O code]
- Cholangiocarcinoma [ICD-11 Extension code]
- Cholangiocarcinoma [HPO term]
- Cholangiocarcinoma (morphologic abnormality) [SNOMED CT concept]
- Cholangiocarcinoma NOS [MedDRA LLT]
- Cholangiocarcinoma of biliary tract (disorder) [SNOMED CT concept]
- Intrahepatic Cholangiocarcinoma [MeSH concept]
- Intrahepatic bile duct carcinoma [ICD-10 Sub-category]
- Intrahepatic bile duct carcinoma [ICD-10 Sub-category (who)]
- Intrahepatic bile duct carcinoma [MedDRA LLT]
- Intrahepatic bile duct carcinoma (disorder) [SNOMED CT concept]
- Intrahepatic cholangiocarcinoma [MedDRA LLT]
- Intrahepatic cholangiocarcinoma [ICD-11 Sub-sub category]
- cholangiocarcinoma [MeSH Descriptor]
- cholangiocarcinoma [Disease (Nov.)]
- cholangiocarcinoma [SNOMED Notion]
- cholangiocarcinoma [MeSH concept]
- cholangiocarcinoma [Radlex concept]
- cholangiocarcinoma [DO Concept]
- cholangiocellular carcinoma [Radlex concept]
- intrahepatic cholangiocarcinoma [Radlex concept]
- intrahepatic cholangiocarcinoma [DO Concept]
DO Cross reference
- intrahepatic cholangiocarcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease excludes normal cell origin
- Embryonic Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Malaise [NCIt concept]
- Thorotrast Exposure [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
- Weight Loss [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
Has associated anatomic sites
- Bile Duct [NCIt concept]
- Biliary Tract [NCIt concept]
- Digestive System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Cholangiocarcinoma of intrahepatic biliary tract (disorder) [SNOMED CT concept]
- Intrahepatic bile duct carcinoma [MedDRA LLT]
- Intrahepatic bile duct carcinoma [ICD-10 Sub-category]
- Intrahepatic bile duct carcinoma [ICD-10 Sub-category (who)]
- Intrahepatic bile duct carcinoma (disorder) [SNOMED CT concept]
- Intrahepatic cholangiocarcinoma [MedDRA LLT]
- Intrahepatic cholangiocarcinoma [ICD-11 Sub-sub category]
- intrahepatic cholangiocarcinoma [Radlex concept]
- intrahepatic cholangiocarcinoma [DO Concept]
Validated automatic mappings to NTBT
- intrahepatic bile duct cancer [Disease (Nov.)]
concept_is_in_subset
- CDISC SEND Terminology [NCIt concept]
- CDISC SEND Tumor Findings Results Terminology [NCIt concept]
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- mCode Cancer Disorder Value Set [NCIt concept]
- mCode Elixhauser Malignant Solid Tumors without Metastases Value Set [NCIt concept]
- mCode Primary Cancer Disorder Value Set [NCIt concept]
- mCode Primary Malignant Neoplasm Disorder Value Set [NCIt concept]
- mCode Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Fibrotic Stroma Formation [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Bile Duct Epithelium [NCIt concept]
- Epithelial Tissue [NCIt concept]
- Hepatobiliary Tissue [NCIt concept]
- Intrahepatic Bile Duct Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Bile Duct [NCIt concept]
- Biliary Tract [NCIt concept]
- Digestive System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Intrahepatic Bile Duct [NCIt concept]
- Liver [NCIt concept]
- Pancreatobiliary System [NCIt concept]
disease_may_have_molecular_abnormality
- KRAS Gene Amplification [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

Keyword's position in hierarchy(ies) :

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