Cefotaxime - CISMeF

Preferred Label : Cefotaxime;

NCIt definition : A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis.;

UNII : N2GI8B1GK7;

InChIKey : GPRBEKHLDVQUJE-QSWIMTSFSA-N;

CAS number : 63527-52-6;

Chemical formula : C16H17N5O7S2;

ChEBI ID : CHEBI:204928;

Details

Origin ID

C354;

UMLS CUI

C0007554;

Currated CISMeF NLP mapping
- Cefotaxime [ICD-11 Extension code]
- Cefotaxime [ICHI extension code]
- Cefotaxime [SMS substance]
- Cefotaxime [LOINC component]
- Cefotaxime (substance) [SNOMED CT concept]
- Cefotaxime.meningitis [OBSOLETE LOINC component]
- cefotaxime [Substance BNPC]
- cefotaxime [MeSH Descriptor]
- cefotaxime [MeSH concept]
- cefotaxime [SNOMED Notion]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefotaxime [ICD-11 Extension code]
- Cefotaxime [LOINC component]
- Cefotaxime (substance) [SNOMED CT concept]
- Product containing cefotaxime (medicinal product) [SNOMED CT concept]
- cefotaxime [ATC Code]
- cefotaxime [Substance BNPC]
- cefotaxime [MeSH concept]
- cefotaxime [SNOMED Notion]
- cefotaxime [MeSH Descriptor]
Validated automatic mappings to BTNT
- cefotaxime [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Cefotaxime Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Cefotaxime Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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