NCIt synonyms : Sheehan's Syndrome; Postpartum Hypopituitarism; Sheehan s Syndrome;
NCIt definition : An uncommon cause of hypopituitarism seen after severe postpartum hemorrhaging. Prolonged
hypovolemia leads to ischemic necrosis of the pituitary. Clinical signs typically
present in the puerperium and include failure to begin lactation, fatigue, hypotension
and eventual amenorrhea. Clinical course is usually mild, however extreme cases may
progress to adrenal failure. Prognosis is most favorable when hormone replacement
is initiated soon after symptom onset.;