Nephrotic Syndrome with Lesion of Membranoproliferative Glomerulonephritis - CISMeF
Nephrotic Syndrome with Lesion of Membranoproliferative GlomerulonephritisNCIt concept
Preferred Label : Nephrotic Syndrome with Lesion of Membranoproliferative Glomerulonephritis;
NCIt synonyms : Nephrotic Syndrome with Lesion of Mesangiocapillary Glomerulonephritis; Nephrotic Syndrome with Lesion of Lobular Glomerulonephritis;
NCIt definition : A renal functional disorder characterized by proteinuria, edema, hyperlipidemia and
hypoalbuminemia. It results from damage to the renal vascular filtration apparatus.
It is further characterized by an inflammatory reaction of the glomerular capillaries
due to the proliferation of mesangial cells, expansion of the mesangial matrix and
deposition of immune complexes causing subsequent thickening of the glomerular basement
membrane. Sequelae may include hypertension, atherosclerosis, infection, hypercoagulablity
and renal failure.;