Carubicin - CISMeF

Preferred Label : Carubicin;

NCIt synonyms : Demethyldaunomycin; Carminomycin I; Karminomitsin; (2S,3S)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,10,12-tetrahydroxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside; CMM; Karminomycin; 4-O-demethyldaunorubicin; 5,12-naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetra-hydroxy-,(8S-cis)-(8CI)-(9CI); (8S-cis)-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione; 5,12-naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetra-hydroxy-(8S-cis)-(8CI 9CI);

NCIt related terms : CARMINOMYCIN; 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3, 6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9, 10-tetrahydro-1,6,8,11-tetra-hydroxy- (8S-cis)- (8CI 9CI);

NCIt definition : An anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.;

UNII : E7437K3983;

InChIKey : XREUEWVEMYWFFA-CSKJXFQVSA-N;

CAS number : 50935-04-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 50935-04-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C26H27NO10;

NSC code : 180024;

Codes from synonyms : NSC0180024;

Details

Origin ID

C352;

UMLS CUI

C0007308;

Automatic exact mappings (from CISMeF team)
- Melanoma, cutaneous malignant, susceptibility to, 1 [OMIM Phenotype]
- myoelectric complex, migrating [MeSH Descriptor]
Currated CISMeF NLP mapping
- carubicin [MeSH Descriptor]
- carubicin [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- carubicin [MeSH Descriptor]
- carubicin [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Carubicin Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Carubicin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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