Atypical Chronic Myeloid Leukemia

Preferred Label : Atypical Chronic Myeloid Leukemia;

NCIt synonyms : Atypical CML; aCML; Subacute Granulocytic Leukemia; Atypical Chronic Myeloid Leukemia, BCR::ABL1 Negative; Myelodysplastic/Myeloproliferative Neoplasm with Neutrophilia; MDS/MPN-N;

NCIt related terms : Subacute myelogenous leukemia; Subacute myeloid leukemia; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative;

NCIt definition : A myelodysplastic/myeloproliferative neoplasm characterized by the presence of leukocytosis with increased numbers of neutrophils, promyelocytes, myelocytes, and metamyelocytes; blasts less than 20% in bone marrow and peripheral blood; dysgranulopoiesis; minimal or absent monocytosis; absence of eosinophilia; and presence of bone marrow hypercellularity with granulocytic proliferation and granulocytic dysplasia. Dysplasia in the erythroid and megakaryocytic lineages may be present or absent. No evidence of BCR/ABL fusion is present.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1779346;

ICD-O code : 9876/3;

Details

Origin ID

C3519;

UMLS CUI

C1292772;

Automatic exact mappings (from CISMeF team)
- Leukemia, chronic myeloid [OMIM Phenotype]
- Myeloid leukemia, subacute [ICD-9 code]
- Subacute myeloid leukaemia [ICD-11 Extension code]
- Subacute myeloid leukemia [ICD-9 code]
- leukemia, myeloid, chronic, atypical, BCR-ABL negative [MeSH concept]
- leukemia, myeloid, chronic, atypical, bcr-abl negative [MeSH Descriptor]
- subacute myeloid leukemia [DO Concept]
Currated CISMeF NLP mapping
- Atypical chronic myeloid leukaemia, BCR-ABL1- negative [ICD-11 Category]
- Atypical chronic myeloid leukemia [ORDO Disease]
- Atypical chronic myeloid leukemia, BCR/ABL-negative [ICD-10 Sub-category]
- Myeloid leukaemia, subacute [MedDRA LLT]
- Myeloid leukemia, subacute [MedDRA LLT]
- Subacute myeloid leukaemia [ICD-10 Sub-category (who)]
- Subacute myeloid leukaemia [MedDRA LLT]
- Subacute myeloid leukemia [MedDRA LLT]
- atypical chronic myeloid leukemia [DO Concept]
DO Cross reference
- atypical chronic myeloid leukemia [DO Concept]
Disease excludes abnormal cell
- Toxic Neutrophil [NCIt concept]
Disease may have findings
- Hepatomegaly [NCIt concept]
- Splenomegaly [NCIt concept]
- Thrombocytopenia [NCIt concept]
False automatic mappings
- Myelodysplastic-myeloproliferative neoplasm with neutrophilia (disorder) [SNOMED CT concept]
- Subacute myeloid leukaemia (in remission) [MedDRA LLT]
- Subacute myeloid leukemia (disorder) [SNOMED CT concept]
- Subacute myeloid leukemia (in remission) [MedDRA LLT]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Atypical chronic myeloid leukaemia, BCR-ABL1- negative [ICD-11 Category]
- Atypical chronic myeloid leukemia [ORDO Disease]
- Atypical chronic myeloid leukemia, BCR/ABL negative [ICD-O code]
- Atypical chronic myeloid leukemia, BCR/ABL-negative [ICD-10 Sub-category]
- Myelodysplastic and myeloproliferative neoplasm with neutrophilia (morphologic abnormality) [SNOMED CT concept]
- Myelodysplastic-myeloproliferative neoplasm with neutrophilia (disorder) [SNOMED CT concept]
- Myeloid leukaemia, subacute [MedDRA LLT]
- Myeloid leukemia, subacute [ICD-9 code]
- Myeloid leukemia, subacute [MedDRA LLT]
- Subacute myeloid leukaemia [MedDRA LLT]
- Subacute myeloid leukaemia without mention of remission [MedDRA LLT]
- Subacute myeloid leukemia [MedDRA LLT]
- Subacute myeloid leukemia (disorder) [SNOMED CT concept]
- Subacute myeloid leukemia without mention of remission [MedDRA LLT]
- atypical chronic myeloid leukemia [DO Concept]
- leukemia, myeloid, chronic, atypical, BCR-ABL negative [MeSH concept]
- leukemia, myeloid, chronic, atypical, bcr-abl negative [MeSH Descriptor]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_cytogenetic_abnormality
- Philadelphia Chromosome [NCIt concept]
- t(9;22)(q34.1;q11.2) [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Extramedullary Hematopoiesis [NCIt concept]
disease_excludes_molecular_abnormality
- BCR-ABL1 Fusion Protein Expression [NCIt concept]
- PDGFRA Gene Rearrangement [NCIt concept]
- PDGFRB Gene Rearrangement [NCIt concept]
disease_has_abnormal_cell
- Dysplastic Megakaryocyte [NCIt concept]
- Dysplastic Neutrophil [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_associated_gene
- CCDC6 Gene [NCIt concept]
- CCDC6 wt Allele [NCIt concept]
- NRAS Gene [NCIt concept]
- NRAS wt Allele [NCIt concept]
disease_has_finding
- Blasts Under 20 Percent of Bone Marrow Nucleated Cells [NCIt concept]
- Blasts Under 20 Percent of Peripheral Blood White Cells [NCIt concept]
- Bone Marrow Dysplasia Present [NCIt concept]
- Hypercellular Bone Marrow [NCIt concept]
- Immature Granulocytes in Peripheral Blood Increased [NCIt concept]
- Leukocytosis [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neutrophilia [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Myeloid Stem Cell [NCIt concept]
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_abnormal_cell
- Dysplastic Erythroid Precursor [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 13 [NCIt concept]
- Gain of Chromosome 8 [NCIt concept]
- Loss of Chromosome 12p [NCIt concept]
- Loss of Chromosome 20q [NCIt concept]
disease_may_have_molecular_abnormality
- NRAS Gene Mutation [NCIt concept]
may_be_associated_disease_of_disease
- Philadelphia Chromosome Negative BCR-ABL1 Negative Chronic Myelogenous Leukemia [NCIt concept]

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