NCIt synonyms : Thromboangiitis Obliterans; Buerger's Disease; Buerger s Disease;
NCIt related terms : Thromboangiitis obliterans [Buerger's disease];
NCIt definition : An inflammatory vascular disorder that affects small and medium-sized arteries and
veins in the extremities. The inflammatory process is initiated in the tunica intima
and results in thrombosis and vascular obstruction with subsequent ischemia and ulceration
of the limbs and digits. It affects males more often than females and usually occurs
at age 20-45 years. It is strongly associated with heavy tobacco use.;