NCIt definition : An inflammatory process affecting the kidney. The cause is most often bacterial, but
may also be fungal in nature. Signs and symptoms may include fever, chills, flank
pain, painful and frequent urination, cloudy or bloody urine, and confusion.;
Alternative definition : NICHD: An infection of the kidney.; CTCAE: A disorder characterized by an infectious process involving the kidney.; CDISC: A tubulointerstitial inflammatory disease involving a spectrum of lesions affecting
the tubules, interstitium and/or the pelvis of the kidney. Pyelonephritis can result
from infections, both ascending and descending and following papillary necrosis and
urothelial ulceration. Certain strains of rodents are particularly susceptible to
developing spontaneous pyelonephritis and are used as animal models to assess antibiotic
therapy. (INHAND); FDA: An inflammatory process affecting the kidney.;