" /> Carmustine - CISMeF





Preferred Label : Carmustine;

NCIt synonyms : Carmustin; Bis-Chloronitrosourea; 1,3-Bis(2-chloroethyl)-1-nitrosourea; 1,3-Bis(beta-chloroethyl)-1-nitrosourea; Bis(chloroethyl) Nitrosourea;

NCIt related terms : N,N'-Bis(2-chloroethyl)-N-nitrosourea; BCNU; Carmubris; Nitrumon;

NCIt definition : An antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called alkylating agents.;

UNII : U68WG3173Y;

InChIKey : DLGOEMSEDOSKAD-UHFFFAOYSA-N;

CAS number : 154-93-8;

Drug name : Carmustinum; Becenun; Carmubris; Nitrourean; Becenum; BiCNU; Nitrumon;

Molecule name : WR-139021; FDA 0345; SRI 1720; SK 27702; NSC 409962; WR 139021; NSC409962;

Chemical formula : C5H9Cl2N3O2;

NSC code : 409962;

ChEBI ID : CHEBI:3423;

Codes from synonyms : CDR0000045976; NSC0409962; 90;

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01/06/2025


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