" /> Carmustine - CISMeF





Preferred Label : Carmustine;

NCIt synonyms : Carmustin; Bis-Chloronitrosourea; 1,3-Bis(2-chloroethyl)-1-nitrosourea; 1,3-Bis(beta-chloroethyl)-1-nitrosourea; Bis(chloroethyl) Nitrosourea;

NCIt related terms : N,N'-Bis(2-chloroethyl)-N-nitrosourea; BCNU; Carmubris; Nitrumon;

NCIt definition : An antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called alkylating agents.;

UNII : U68WG3173Y;

InChIKey : DLGOEMSEDOSKAD-UHFFFAOYSA-N;

CAS number : 154-93-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 154-93-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Carmustinum; Becenun; Carmubris; Nitrourean; Becenum; BiCNU; Nitrumon;

Molecule name : WR-139021; FDA 0345; SRI 1720; SK 27702;

Chemical formula : C5H9Cl2N3O2;

NSC code : 409962;

ChEBI ID : CHEBI:3423;

Codes from synonyms : CDR0000045976; NSC0409962; 90;

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15/05/2024


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