NCIt definition : A circumscribed inflammatory and often suppurating lesion on the skin or an internal
mucous surface resulting in necrosis of tissue.;
Alternative definition : NICHD: A circumscribed loss of integrity of the skin or mucous membrane.; CDISC: Destruction of an epithelial surface extending into or beyond the basement
membrane.; FDA: An open sore on an external or internal surface of the body caused by a break
in the skin or mucous membrane that fails to heal.;