NCIt synonyms : Diffuse Giant Cell Tumor of Tenosynovium; Diffuse Giant Cell Neoplasm of Tendon Sheath; Pigmented Villonodular Synovitis; Diffuse Tenosynovial Giant Cell Tumor; Diffuse Giant Cell Tumor of the Tenosynovium; Diffuse Tenosynovial Giant Cell Neoplasm; Diffuse Giant Cell Neoplasm of the Tenosynovium; Diffuse Giant Cell Neoplasm of Tenosynovium; Diffuse Giant Cell Tumor of Tendon Sheath;
NCIt definition : A locally aggressive, diffusely infiltrating tumor, arising in the tendon sheath.
It is composed of synovial-like mononuclear cells, hemosiderin-laden macrophages,
foam cells, and inflammatory cells. Multinucleated osteoclast-like giant cells are
usually present, although in a minority of cases they may be absent or rare. It predominantly
affects young adults. Symptoms include joint swelling, pain, and joint effusion.;