" /> Peginterferon Alfa-2a - CISMeF





Preferred Label : Peginterferon Alfa-2a;

NCIt synonyms : Pegylated Interferon Alfa-2a;

NCIt related terms : PEG-interferon alfa-2a; Pegasys;

NCIt definition : A covalent conjugate of recombinant interferon alfa, subtype 2a, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The biological activity of this agent is derived from its interferon alpha-2a protein moiety. Interferons alfa bind to specific cell-surface receptors, leading to the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer and immune-modulating effects. The PEG moiety lowers the clearance of interferon alpha-2a, thereby extending the duration of its therapeutic effects, but may also reduce interferon-mediated stimulation of an immune response. (NCI04);

Alternative definition : NCI-GLOSS: A drug used to treat hepatitis C infections. It is also being studied in the treatment and prevention of cancer. It is a cytokine that is modified in the laboratory. It is a type of biological response modifier.;

UNII : Q46947FE7K;

CAS number : 198153-51-4;

Drug name : Pegasys;

Chemical formula : C10H18N3O5(C2H4O)n(C2H4O)n;

NSC code : 729130;

Codes from synonyms : CDR0000346467; CDR0000410751; 391;

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28/05/2025


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