Preferred Label : Intermediate Type Trophoblastic Cell;
NCIt synonyms : Intermediate Trophoblast;
NCIt definition : A trophoblast that travels into the junctional zone of the decidua, reacting with
maternal tissue leukocytes, mainly NK cells, macrophages and T cells, and invades
maternal blood vessels feeding the placenta, softening the walls and replacing the
lining with fetal tissue. This junctional zone extends at the edge of the placenta
to the amino-chorionic membranes where the chorionic laeve trophoblast has intimate
contact with decidua tissue. One of the primary functions of this cell is in implantation
and in the establishment of the uteroplacental circulation since it extensively invades
the spiral arteries at the placental site.;