Preferred Label : Annona muricata;
NCIt synonyms : Prickly Custard Apple; Brazilian Cherimoya; Brazilian Paw Paw; Guanabana; Soursop; Graviola;
NCIt related terms : ANNONA MURICATA WHOLE;
NCIt definition : A common name for the tropical tree Annona muricata whose tissues contain annonaceous
acetogenins, compounds with antineoplastic activity. Annonaceous acetogenins, derivatives
of long-chain fatty acids, exhibit their anti-tumor properties by depleting cellular
stores of adenosine 5'-triphosphate (ATP), a primary source of energy in cells. These
agents also inhibit ATP-driven drug resistance mechanisms. Possessing a broad range
of therapeutic activities, graviola has been used in different cultures for its pesticidal,
antifungal,, antispasmodic, anticonvulsant, vasodilator, smooth-muscle relaxant, and
hypotensive properties. (NCI04);
UNII : AN924793RM;
Taxon ID : 13337;
Origin ID : C33900;
UMLS CUI : C1000635;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- Plant [UMLS semantic type]
- concept_is_in_subset
