Large Intestinal Glandular Cell

Preferred Label : Large Intestinal Glandular Cell;

NCIt definition : Intestinal enterocytes are low columnar to cuboidal cells comprising the majority of the epithelial tissue in the intestine and colon. They have both absorptive and secretory functions, absorbing water, sodium and short-chain fatty acids while secreting bicarbonate and potassium. Colonocytes originate from stem cells located at the base of the crypts. Enterocyte production, differentiation, and turnover occurs in topographically distinct regions of crypts. The transformation of colonic epithelial cells are frequently involved in colorectal cancers.;

Details

Origin ID

C32925;

UMLS CUI

C1517726;

Anatomic structure is physical part of
- Epithelial Tissue [NCIt concept]
- Glandular Epithelial Tissue [NCIt concept]
- Gut Epithelium [NCIt concept]
- Intestine [NCIt concept]
- Large Intestinal Mucosa [NCIt concept]
Automatic exact mappings (from CISMeF team)
- Glandular cell of large intestine [FMA entity]
Semantic type(s)
- Cell [UMLS semantic type]
UMLS correspondences (same concept)
- Glandular cell of large intestine [FMA entity]
is_normal_cell_origin_of_disease
- Attenuated Familial Adenomatous Polyposis [NCIt concept]

Keyword's position in hierarchy(ies) :

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