Leydig Cell Tumor

Preferred Label : Leydig Cell Tumor;

NCIt synonyms : Interstitial Cell Neoplasm; Interstitial Cell Tumor; Leydig Cell Neoplasm;

NCIt definition : A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course.;

Alternative definition : NICHD: A sex cord-stromal tumor, comprising Leydig cells, either predominantly or completely, occurring in the testis and rarely in the ovary.;

Neoplastic status : Undetermined;

ICD-O code : 8650/1;

Details

Origin ID

C3188;

UMLS CUI

C0023601;

Currated CISMeF NLP mapping
- Leydig cell tumor [DO Concept]
- Leydig cell tumor [Disease (Nov.)]
- Leydig cell tumor, benign (morphologic abnormality) [SNOMED CT concept]
- Leydig cell tumor, no International Classification of Diseases for Oncology subtype (morphologic abnormality) [SNOMED CT concept]
- leydig cell tumor [MeSH Descriptor]
- leydig cell tumor [MeSH concept]
- leydig cell tumor, nos [SNOMED Notion]
DO Cross reference
- Leydig cell tumor [DO Concept]
Disease excludes abnormal cell
- Neoplastic Germ Cell [NCIt concept]
- Neoplastic Sertoli Cell [NCIt concept]
- Neoplastic Stromal Cell [NCIt concept]
Disease may have findings
- Reinke Crystals Formation [NCIt concept]
HPO term
- Leydig cell neoplasia [HPO term]
Has associated anatomic sites
- Genitourinary System [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Leydig cell tumor [DO Concept]
- Leydig cell tumor, no International Classification of Diseases for Oncology subtype (morphologic abnormality) [SNOMED CT concept]
- leydig cell tumor [MeSH concept]
- leydig cell tumor [MeSH Descriptor]
- leydig cell tumor, nos [SNOMED Notion]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Hematology-Oncology Terminology [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Leydig Cell [NCIt concept]
- Neoplastic Sex Cord-Stromal Cell [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients