" /> Bleomycin A2 - CISMeF





Preferred Label : Bleomycin A2;

NCIt synonyms : Zhengguangmycin A2; Pingyangmycin A2; N1-(3-(Dimethylsulfonio)propyl)bleomycinamide;

NCIt definition : The primary bleomycin species in bleomycin sulfate, a mixture of the sulfate salts of several basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin A2 forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation. (NCI04);

UNII : 13M89UEA7W;

InChIKey : OYVAGSVQBOHSSS-UAPAGMARSA-N;

CAS number : 11116-31-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 11116-31-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C55H84N17O21S3;

NSC code : 146842;

ChEBI ID : CHEBI:3139;

Codes from synonyms : NSC0146842;

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15/05/2024


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