Eosinophilic Granuloma

Preferred Label : Eosinophilic Granuloma;

NCIt related terms : Unifocal Langerhans Cell Histiocytosis; Monostotic Langerhans Cell Histiocytosis; Chronic Unifocal Langerhans Cell Histiocytosis; Eosinophilic Xanthomatous Granuloma; Unifocal Langerhans-cell histiocytosis;

NCIt definition : A clinical variant of Langerhans cell histiocytosis characterized by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults usually presenting with a lytic bone lesion. The etiology is unknown. Morphologically, eosinophilic granuloma is characterized by the presence of Langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils, and small, mature lymphocytes.;

Alternative definition : NICHD: A clinical variant of Langerhans cell histiocytosis that is characterized by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults, often presenting with a lytic bone lesion of an unknown etiology. Morphologically, eosinophilic granuloma is characterized by the presence of Langerhans cells in a characteristic milieu that includes histiocytes, eosinophils, neutrophils, and small, mature lymphocytes.;

Neoplastic status : Undetermined;

ICD-O code : 9752/1;

Codes from synonyms : C96.6;

Details

Origin ID

C3016;

UMLS CUI

C0014461;

Automatic exact mappings (from CISMeF team)
- Eosinophilic granuloma [ACR pathology]
- Eosinophilic granuloma [ACR pathology]
- Eosinophilic granuloma [ACR pathology]
- Eosinophilic granuloma [ICD-11 Extension code]
- Eosinophilic granuloma [ICD-11 Extension code]
- Eosinophilic granuloma [HPO term]
- Granuloma and granuloma-like lesions of oral mucosa [ICD-10 Sub-category]
- Langerhans cell histiocytosis, not elsewhere classified [ICD-10 Sub-category (who)]
- Langerhans cell histiocytosis, unifocal [ICD-O code]
- Langerhans cell histiocytosis, unifocal [ICD-11 Extension code]
- Unifocal Langerhans-cell histiocytosis [ICD-10 Sub-category]
Currated CISMeF NLP mapping
- EOSINOPHILIC GRANULOMA [WHO-ART Preferred Term]
- Eosinophilic granuloma [PASCAL descriptor]
- Eosinophilic granuloma [MedDRA LLT]
- Eosinophilic granuloma (morphologic abnormality) [SNOMED CT concept]
- eosinophilic granuloma [MeSH Descriptor]
- eosinophilic granuloma [MeSH concept]
- eosinophilic granuloma [Radlex concept]
Disease may have findings
- CD68-Positive Neoplastic Cells Present [NCIt concept]
- Lytic Bone Lesion [NCIt concept]
- Sinusoidal Infiltration [NCIt concept]
False automatic mappings
- Eosinophilic granuloma [ORDO Disease]
- Eosinophilic granuloma (disorder) [SNOMED CT concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- EOSINOPHILIC GRANULOMA [WHO-ART Preferred Term]
- Eosinophilic granuloma [ORDO Disease]
- Eosinophilic granuloma [HPO term]
- Eosinophilic granuloma [MedDRA LLT]
- Eosinophilic granuloma (disorder) [SNOMED CT concept]
- Eosinophilic granuloma (morphologic abnormality) [SNOMED CT concept]
- eosinophilic granuloma [Radlex concept]
- eosinophilic granuloma [MeSH concept]
- eosinophilic granuloma [MeSH Descriptor]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Endocrinology Terminology [NCIt concept]
- Pediatric Hematology-Oncology Terminology [NCIt concept]
- mCode Cancer Disorder Value Set [NCIt concept]
- mCode Primary Cancer Disorder Value Set [NCIt concept]
- mCode Primary Malignant Neoplasm Disorder Value Set [NCIt concept]
- mCode Terminology [NCIt concept]
disease_excludes_finding
- CD21-Positive Neoplastic Cells Present [NCIt concept]
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- CD35-Positive Neoplastic Cells Present [NCIt concept]
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- High Grade Lesion [NCIt concept]
disease_excludes_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gene Rearrangement [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Histiocytic and Dendritic Cell [NCIt concept]
- Neoplastic Langerhans Cell [NCIt concept]
disease_has_finding
- Birbeck Granules Present [NCIt concept]
- CD1a-Positive Neoplastic Cells Present [NCIt concept]
- Histiocytosis [NCIt concept]
- Monoclonal Langerhans Cells Present [NCIt concept]
- Polymorphic Cellular Infiltrate [NCIt concept]
- Rare Lesion [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
- Unifocal Lesion [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Histiocyte [NCIt concept]
- Histiocytic and Dendritic Cell [NCIt concept]
- Langerhans Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]

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