" /> Eosinophilic Granuloma - CISMeF





Preferred Label : Eosinophilic Granuloma;

NCIt related terms : Unifocal Langerhans Cell Histiocytosis; Monostotic Langerhans Cell Histiocytosis; Chronic Unifocal Langerhans Cell Histiocytosis; Eosinophilic Xanthomatous Granuloma; Unifocal Langerhans-cell histiocytosis;

NCIt definition : A clinical variant of Langerhans cell histiocytosis characterized by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults usually presenting with a lytic bone lesion. The etiology is unknown. Morphologically, eosinophilic granuloma is characterized by the presence of Langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils, and small, mature lymphocytes.;

Alternative definition : NICHD: A clinical variant of Langerhans cell histiocytosis that is characterized by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults, often presenting with a lytic bone lesion of an unknown etiology. Morphologically, eosinophilic granuloma is characterized by the presence of Langerhans cells in a characteristic milieu that includes histiocytes, eosinophils, neutrophils, and small, mature lymphocytes.;

Neoplastic status : Undetermined;

ICD-O code : 9752/1;

Codes from synonyms : C96.6;

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30/07/2025


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