Bence Jones Protein

Preferred Label : Bence Jones Protein;

NCIt synonyms : Bence-Jones Protein;

NCIt definition : Human immunoglobulin kappa and/or lambda light chains detected in their free form in serum or urine samples as a result of overproduction by plasma cells due to neoplastic proliferation. Detection of immunoglobulin light chains in concentrations that exceed that of heavy chains is associated with plasma cell neoplasms.;

Alternative definition : NCI-GLOSS: A small protein made by plasma cells (white blood cells that produce antibodies). It is found in the urine of most people with multiple myeloma (cancer that begins in plasma cells).;

Codes from synonyms : CDR0000411371;

Details

Origin ID

C301;

UMLS CUI

C0004965;

Currated CISMeF NLP mapping
- Bence Jones protein (substance) [SNOMED CT concept]
- bence jones protein [MeSH Descriptor]
- bence jones protein [MeSH concept]
- bence jones protein [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Bence Jones protein (substance) [SNOMED CT concept]
- bence jones protein [SNOMED Notion]
- bence jones protein [MeSH Descriptor]
- bence jones protein [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
gene_product_has_biochemical_function
- Antibody [NCIt concept]
gene_product_has_chemical_classification
- Protein or Riboprotein Complex [NCIt concept]
gene_product_is_biomarker_of
- Plasma Cell Neoplasm [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Binding [NCIt concept]
- Immune Response Process [NCIt concept]
- Immune System Process [NCIt concept]
has_gene_product_element
- Immunoglobulin Lambda Constant 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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