NCIt definition : A malignant germ cell tumor characterized by the presence of a monotonous primitive
germ cell population. The neoplastic cells form aggregates and have an abundant pale
cytoplasm and uniform nuclei. The aggregates of the germ cells are separated by fibrous
septa which contain inflammatory cells, mostly T-lymphocytes. It arises primarily
in the ovaries, but can occur both primarily and secondarily at other sites, particularly
the central nervous system. It responds to chemotherapy and radiotherapy. Its prognosis
is related to the tumor stage.;
Alternative definition : NICHD: A seminomatous germ cell tumor originating in the ovary.; CDISC: A malignant germ cell neoplasm characterized by the presence of a monotonous
primitive germ cell population, primarily in the ovary.; NCI-GLOSS: A type of tumor that begins in the type of cells that give rise to egg
cells and is most often found in the ovaries. Dysgerminomas may also occur in other
places in the body, including the central nervous system. They are the most common
type of ovarian germ cell tumor and can spread to other parts of the body. They are
most common in females who are younger than 20 years old.;