Rebamipide - CISMeF

Preferred Label : Rebamipide;

NCIt related terms : alpha-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic Acid;

NCIt definition : A quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.;

UNII : LR583V32ZR;

InChIKey : ALLWOAVDORUJLA-UHFFFAOYSA-N;

CAS number : 90098-04-7; 111911-87-6;

Molecule name : OPC 12759;

Chemical formula : C19H15ClN2O4;

Codes from synonyms : 09339;

Details

Origin ID

C29852;

UMLS CUI

C0069562;

Automatic exact mappings (from CISMeF team)
- Rebamipide [ICD-11 Extension code]
Currated CISMeF NLP mapping
- rebamipide [MeSH concept]
- rebamipide [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing rebamipide (medicinal product) [SNOMED CT concept]
- Rebamipide (substance) [SNOMED CT concept]
- rebamipide [ATC Code]
- rebamipide [MeSH concept]
- rebamipide [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- rebamipide [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients