NCIt definition : A natural or synthetic isoprenoid hydrocarbon (C19) derivative, Pristane is commonly
used in research to prime the abdomen prior to hybridoma implantation in experimental
animals. An irritant that induces granulomatous inflammation and interferes with local
lymphatic drainage, it increases ascitic yields. Pristane has a low margin of safety
and is toxic at levels slightly higher than used to prime animals. (NCI04);