Nimesulide - CISMeF

Preferred Label : Nimesulide;

NCIt synonyms : N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide;

NCIt definition : A nonsteroidal arylsulfonamide with anti-inflammatory properties. Nimesulide inhibits the cyclooxygenase-mediated conversion of arachidonic acid to pro-inflammatory prostaglandins. Modestly selective for COX-2, this agent binds to the enzyme, thereby inactivating it. Nimesulide may inhibit some carcinogenic COX-2-related carcinogenic effects on xenobiotic metabolism, apoptosis, immune surveillance and angiogenesis (overexpressed COX-2 in tumor epithelial cells enhances production of vascular growth factors and the formation of capillary-like networks). (NCI04);

UNII : V4TKW1454M;

InChIKey : HYWYRSMBCFDLJT-UHFFFAOYSA-N;

CAS number : 51803-78-2;

Chemical formula : C13H12N2O5S;

ChEBI ID : CHEBI:44445;

Codes from synonyms : 09322;

Details

Origin ID

C29842;

UMLS CUI

C0132515;

CISMeF manual mappings
- Nimesulide (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nimesulide [ICD-11 Extension code]
- Nimesulide (substance) [SNOMED CT concept]
- Product containing nimesulide (medicinal product) [SNOMED CT concept]
- nimesulide [ATC Code]
- nimesulide [ATC Code]
- nimesulide [Substance BNPC]
- nimesulide [MeSH concept]
- nimesulide [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- nimesulide [ATC Code]
- nimesulide [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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