NCIt definition : A compound used experimentally to induce tumors in animal models of carcinogenesis.
In mice and rats, 1,2-dimethylhydrazine may induce carcinogenesis through deregulation
of the cell cycle. This agent primarily induces gastrointestinal and vascular tumors.
1,2-Dimethylhydrazine may be found in small amounts in the environment due to its
use in industry and agriculture. (NCI04);