19-Norprogesterone

Preferred Label : 19-Norprogesterone;

NCIt synonyms : 19-nor-Progesterone; 19-Nor-P;

NCIt definition : A steroid progestin derivative with antigonadotropic activity. 19-nor-Progesterone decreases luteinizing hormone (LH) and follicle stimulatory hormone (FSH) secretion, which are effects likely mediated through the binding of this agent to the progesterone receptor. The antigonadotropic activity of this hormone results in reinforcement of its antiestrogenic activity, allowing treatment of the clinical hyper-estrogenic symptoms of peri-menopause without negative metabolic or hemostatic effects. 19-nor-Progesterone, in addition to its inhibitory effect on ovulation, induces changes in the endometrium, rendering it resistant to implantation, and in the cervical mucus, rendering it hostile to spermatozoa migration. This agent is also a potent mineralocorticoid. (NCI04);

UNII : 1A5185976G;

CAS number : 472-54-8;

NSC code : 22021;

Details

Origin ID

C29782;

UMLS CUI

C0045076;

Currated CISMeF NLP mapping
- 19-norprogesterone [MeSH concept]
- 19-norprogesterone [MeSH Supplementary Concept]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 19-norprogesterone [MeSH Supplementary Concept]
- 19-norprogesterone [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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