NCIt definition : A synthetic, light sensitive, yellow crystalline solid that is practically insoluble
in water and soluble in diethyl ether, acetone, ethanol, benzene and toluene. It is
not used for any commercial applications and is used only for research purposes, principally
as a marker for exposure to nitro-polycyclic aromatic hydrocarbons from diesel exhaust.
When heated to decomposition, 1-nitropyrene emits toxic fumes of nitrogen oxides.
This compound is found in particulate emissions from combustion products, of which
diesel exhaust is the principle source. The primary route of potential human exposure
to 1-nitropyrene is inhalation. This compound is one of the most abundant mononitroarenes
detected in ambient air. Occupational exposure to 1-nitropyrene occurs primarily in
workers exposed to diesel engine exhaust in the transport industry. It is reasonably
anticipated to be a human carcinogen. (NCI05);