" /> Sulfonamide Anti-Infective Agent - CISMeF





Preferred Label : Sulfonamide Anti-Infective Agent;

NCIt synonyms : Sulfonamides;

NCIt related terms : sulfonamide; sulfa drug;

NCIt definition : A class of natural or synthetic sulfanilamide derivatives with antibacterial activity. Sulfonamides are structural analogs of para-aminobenzoic acid (essential for microbial folate synthesis). Sulfonamides inhibit bacterial metabolism by competing with PABA for dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately DNA synthesis.;

Alternative definition : NCI-GLOSS: A type of antibiotic used to treat infection.;

NCI Metathesaurus CUI : CL557618;

Codes from synonyms : CDR0000367475; CDR0000367474;

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10/05/2025


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