Preferred Label : Alpha-Adrenergic Antagonist;
NCIt synonyms : Alpha Blocker; Alpha-adrenergic Blocking Agent;
NCIt related terms : alpha-blocker;
NCIt definition : Natural or synthetic Alpha-adrenergic Blocking Agents selectively bind to adrenergic
receptors, or compete with natural adrenergic mediators, and inactivate alpha adrenergic
receptors of the sympathetic nervous system. These agents block the action of natural
sympathomimetic neurotransmitters (norepinephrine and related substances), and can
initiate physiological responses such as vasodilation, bradycardia, and pupil contraction.;
Alternative definition : NCI-GLOSS: A substance that relaxes muscle tissue in blood vessels and in the prostate
gland, which improves the flow of urine and blood. Alpha-blockers are used to treat
the symptoms of many conditions, such as benign prostatic hyperplasia (BPH), high
blood pressure, and some blood circulation problems.;
ChEBI ID : CHEBI:37890;
Codes from synonyms : CDR0000651174; CDR0000651173;
Origin ID : C29713;
UMLS CUI : C0001641;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
