Histamine-2 Receptor Antagonist

Preferred Label : Histamine-2 Receptor Antagonist;

NCIt synonyms : H2 Receptor Antagonist; H2 Antagonist;

NCIt related terms : H2 Blockers; H2 Blocker;

NCIt definition : Any agent that competitively binds to and blocks the histamine H2 receptors found in the stomach, heart, uterus, on vascular smooth muscle and in the central nervous system (CNS). Of particular clinical relevance is the blockage of H2 receptors found on the parietal cells of the stomach, which prevents gastric acid secretion.;

Alternative definition : NICHD: A pharmaceutical agent that blocks the binding of histamine to the type II histamine receptor, and is often used to decrease gastric acid production and to treat urticaria.;

ChEBI ID : CHEBI:37961;

Details

Origin ID

C29702;

UMLS CUI

C0019593;

Automatic exact mappings (from CISMeF team)
- Antagonist H2 receptor [ICHI extension code]
- h2-receptor antagonists [ATC Code]
- histamine H2 antagonists [Artificial nutrition thesaurus concept]
- histamine h2 antagonists [MeSH Descriptor]
Currated CISMeF NLP mapping
- Histamine H2-receptor antagonists [Bloc CIM-11]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Histamine H2-receptor antagonists [Bloc CIM-11]
- Product containing histamine H2 receptor antagonist (product) [SNOMED CT concept]
- Substance with histamine H2 receptor antagonist mechanism of action (substance) [SNOMED CT concept]
- histamine H2 antagonists [MeSH concept]
- histamine h2 antagonists [MeSH Descriptor]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Rheumatology Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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