Preferred Label : Cushing Syndrome;
NCIt synonyms : Cushing's Syndrome; Cushing s Syndrome;
NCIt related terms : Hypercortisolism; Cortisol Excess;
NCIt definition : A syndrome caused by high levels of cortisol in the blood either due to excessive
production and secretion of corticosteroids secondary to pituitary or adrenocortical
neoplasms, or intake of glucocorticoid drugs. Signs and symptoms include a round face,
upper body obesity, fragile and thin skin, purple stretch marks in the skin, fatigue,
muscle weakness, hypertension, diabetes mellitus, hypertrichosis and amenorrhea in
women, impotence in men, and osteoporosis.;
Alternative definition : NICHD: A clinical condition characterized by variable degrees of central obesity,
rounding of the face (moon face), hypertension, striae, and a number of other physical
findings, as a result of prolonged exposure to supranormal cortisol concentration
of any etiology.; NCI-GLOSS: A condition in which there is too much cortisol (a hormone made by the
outer layer of the adrenal gland) in the body. Cushing syndrome may be caused by taking
too many steroid drugs or by certain types of tumors. Tumors that make adrenocorticotropic
hormone (ACTH) cause the adrenal gland to make too much cortisol. Symptoms of Cushing
syndrome include a round face, thin arms and legs, severe fatigue and muscle weakness,
high blood pressure, high blood sugar, purple or pink stretch marks on the skin, and
weight gain, especially in the abdomen.;
Codes from synonyms : CDR0000626500;
Origin ID : C2969;
UMLS CUI : C0010481;
Currated CISMeF NLP mapping
- DO Cross reference
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- may_be_associated_disease_of_disease
