gp100 Peptide-sensitized Autologous T-cells (CD4 and CD8 )

Preferred Label : gp100 Peptide-sensitized Autologous T-cells (CD4 and CD8 );

NCIt synonyms : gp100 Peptide-sensitized Autologous T-cells CD4 plus and CD8 plus;

NCIt definition : A population of CD4 and CD8 T-cells isolated from a cancer patient that have been sensitized in vitro to the melanoma-associated antigen gp100. Infusion of gp100 peptide-sensitized autologous T-cells into the cancer patient may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against gp100-positive tumor cells, thereby decreasing tumor growth. (NCI04);

NSC code : 723494;

Details

Origin ID

C29556;

UMLS CUI

C1515636;

Semantic type(s)
- Cell [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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