Zolimomab Aritox

Preferred Label : Zolimomab Aritox;

NCIt synonyms : H65-RTA; Anti-T-Cell Ricin A Chain Immunotoxin; Anti-T-Cell RTA Immunotoxin; CD5-Immunoconjugate; Anti-CD5 MoAb; Anti-CD5 T-Lymphocyte Immunotoxin; XomaZyme-CD5 Plus; Immunoglobulin G 1 (Mouse Monoclonal H65-RTA Anti-human Antigen CD 5 Heavy Chain), Disulfide with Mouse Monoclonal H65-RTA Light Chain, Dimer, Disulfide with Ricin (Castor-oil Plant A-chain Protein Moiety);

NCIt definition : An immunotoxin consisting of a murine anti-CD5 monoclonal antibody conjugated to the ricin A chain. The anti-CD5 monoclonal antibody component binds to CD5, a T-cell associated antigen, thereby targeting the delivery of the cytotoxic ricin A chain to T-cells. The ricin A chain component binds to T-cells and disrupts ribosomal activity and protein synthesis and induces cell cycle arrest. (NCI04);

UNII : 2C1ZT922TD;

CAS number : 141483-72-9;

Drug name : Orthozyme-CD5 Plus;

NSC code : 620860;

Details

Origin ID

C29549;

UMLS CUI

C0287024;

Automatic exact mappings (from CISMeF team)
- H65-RTA [MeSH concept]
Currated CISMeF NLP mapping
- XomaZyme-CD5 plus [MeSH concept]
- zolimomab aritox [MeSH concept]
- zolimomab aritox [MeSH Supplementary Concept]
See also inter- (CISMeF)
- XomaZyme [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- zolimomab aritox [MeSH concept]
- zolimomab aritox [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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