" /> Uniroyal Compound-38 - CISMeF





Preferred Label : Uniroyal Compound-38;

NCIt synonyms : Uniroyal Jr.; 2-Chloro-5-(((1-methylethoxy)thioxomethyl)amino)benzoic acid; 1-methylethyl-2-chloro-5-[[5,6-dihydro-2-methyl- 1, 4-oxathiin-3-yl-carbonyl]-amino]benzoate; Uniroyal Compound;

NCIt definition : A second generation non-nucleoside reverse transcriptase inhibitor derivative of oxathiin carboxanilide. Uniroyal compound 38 has activity against a wide range of biologically diverse laboratory and clinical strains of HIV-1 but is inactive against HIV-2.;

NCIt note : Compounds owned by Uniroyal, related to UC10 have been shown to be active against virus containing all five of the major mutations that confer resistance to other NNRTIs. Uniroyal's NNRTIs are currently named UC-10 (NSC 645129), UC-40, UC-42, UC-84 (NSC 615985) and UC-781. http://hiv-web.lanl.gov/content/hiv-db/REVIEWS/Mellors.html;

CAS number : 135812-34-9;

Molecule name : UC-38;

NSC code : 615985;

PubMed : 9772165;

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29/05/2025


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