NCIt definition : A second generation non-nucleoside reverse transcriptase inhibitor derivative of oxathiin
carboxanilide. Uniroyal compound 38 has activity against a wide range of biologically
diverse laboratory and clinical strains of HIV-1 but is inactive against HIV-2.;
NCIt note : Compounds owned by Uniroyal, related to UC10 have been shown to be active against
virus containing all five of the major mutations that confer resistance to other NNRTIs.
Uniroyal's NNRTIs are currently named UC-10 (NSC 645129), UC-40, UC-42, UC-84 (NSC
615985) and UC-781. http://hiv-web.lanl.gov/content/hiv-db/REVIEWS/Mellors.html;