NCIt definition : A synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced
gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal
keratinocyte differentiation and reduces their hyperproliferation. (NCI04);
Alternative definition : NCI-GLOSS: A drug used on the skin to treat several skin conditions. It is also being
studied in the treatment of basal cell skin cancer and basal cell nevus syndrome.
Tazarotene is related to vitamin A and is made in the laboratory. It turns on a gene
that may help stop the growth of skin cancer cells. Tazarotene is a type of synthetic
retinoid.;
UNII : 81BDR9Y8PS;
InChIKey : OGQICQVSFDPSEI-UHFFFAOYSA-N;
CAS number : 118292-40-3;
Drug name : Avage; Tazorac;
Molecule name : AGN-190168;
Chemical formula : C21H21NO2S;
ChEBI ID : CHEBI:32184;
Codes from synonyms : CDR0000559445; CDR0000589422; CDR0000589421; 20325;