Rifamycin - CISMeF

Preferred Label : Rifamycin;

NCIt synonyms : Rifamycin SV; 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-B)furan-1,11(2h)-dione 21-Acetate;

NCIt definition : A natural antibiotic produced by Streptomyces mediterranei, Rifamycin (Ansamycin Family) is a commonly used antimycobacterial drug that inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis; it blocks RNA-polymerase transcription initiation. Rifamycin has an activity spectrum against Gram-positive and Gram-negative bacteria, but is mainly used against Mycobacterium sp. (especially M. tuberculosis) in association with other agents to overcome resistance. (NCI04);

UNII : DU69T8ZZPA;

InChIKey : HJYYPODYNSCCOU-ODRIEIDWSA-N;

CAS number : 6998-60-3;

Molecule name : M-14;

Chemical formula : C37H47NO12;

NCI Metathesaurus CUI : CL560681;

NSC code : 145604;

ChEBI ID : CHEBI:26580;

Details

Origin ID

C29406;

UMLS CUI

C0073371;

Automatic exact mappings (from CISMeF team)
- rifamycin [ATC Code]
- rifamycin [ATC Code]
- rifamycin, 1,4-dideoxy-1,4-dihydro-1,4-dioxo- [Substance BNPC]
- rifamycin, 4-o-(carboxymethyl)- [Substance BNPC]
- rifamycin, 4-o-(carboxymethyl)-1-deoxy-1,4-dihydro-4-hydroxy-1-oxo-, .gamma.-lactone [Substance BNPC]
False automatic mappings
- Rifamycins [ICD-10 Sub-category (who)]
- Rifamycins [ICD-10 Sub-category (who)]
- rifamycin SV [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Medicinal product containing rifamycin structure and acting as antibacterial agent (product) [SNOMED CT concept]
- Product containing rifamycin (medicinal product) [SNOMED CT concept]
- Rifamycin (substance) [SNOMED CT concept]
- rifamycin [ATC Code]
- rifamycin [ATC Code]
- rifamycin [ATC Code]
- rifamycin [ATC Code]
- rifamycin [ATC Code]
- rifamycin SV [MeSH Supplementary Concept]
- rifamycin SV [MeSH concept]
Validated automatic mappings to BTNT
- rifamycin [ATC Code]
- rifamycin [ATC Code]
- rifamycin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Rifamycin Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Rifamycin Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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