NCIt definition : The potassium salt form of citrate, with alkalinizing activity and that can be used
for potassium supplementation. Upon oral administration, potassium citrate provides
potassium. Potassium maintains normal fluid and electrolyte balance, regulates the
proper functioning of heart and muscle contractions, supports healthy bone density
and blood pressure. It also plays an important role in the transmission of nerve impulses
and energy production. Amino acid chelated minerals are highly bioavailable and better
absorbed than non-amino acid-chelated minerals. Potassium citrate also causes increased
plasma bicarbonate concentration, thereby raising blood and urinary pH. A simultaneous
decrease in calcium ion activity occurs as a result of increasing calcium complex
formation with dissociated anions. Levels of urinary citrate are increased due to
modification of the renal handling of citrate. By promoting excretion of free bicarbonate
ion and by increasing urinary pH in addition to an increased ionization of uric acid
to more soluble urate ions, this agent exerts alkalizing and anti-urolithic effect.;