Prospidium Chloride

Preferred Label : Prospidium Chloride;

NCIt synonyms : Prospidin; Prospidine; 3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, dichloride;

NCIt definition : An dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophage. Prospidin has good anti-lupus activity due to its immunosuppressive effects and was also used in refractory rheumatoid arthritis as an anti-rheumatic drug. (NCI04);

UNII : 7G733H6RES;

InChIKey : QZJPEEOEZVHUAE-UHFFFAOYSA-L;

CAS number : 23476-83-7;

Chemical formula : C18H36Cl2N4O2.2Cl;

NSC code : 166100;

Details

Origin ID

C29333;

UMLS CUI

C2355570;

Automatic exact mappings (from CISMeF team)
- prospidium [MeSH concept]
- prospidium [MeSH Descriptor]
Currated CISMeF NLP mapping
- prospidium chloride [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- prospidium chloride [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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