Purified Protein Derivative

Preferred Label : Purified Protein Derivative;

NCIt synonyms : PPD Tine Test;

NCIt related terms : PPD;

CISMeF acronym : PPD;

NCIt definition : A purified protein extract derived from the bacterium Mycobacterium tuberculosis. Intradermally-administered, PPD stimulates preprimed CD4 T cells in immunologically competent subjects previously exposed to the bacterium Mycobacterium tuberculosis; these activated CD4 T cells secrete various cytokines that attract granulocytes, monocytes, and macrophages in an inflammatory response known as delayed hypersensitivity. (NCI04);

Alternative definition : NICHD: An extract derived from the supernatant of a culture of Mycobacterium tuberculosis grown under standardized conditions that is used in the tuberculin skin test.;

CAS number : 725-12-2;

Drug name : Tubersol;

NSC code : 53152;

Details

Origin ID

C29329;

UMLS CUI

C0034131;

Currated CISMeF NLP mapping
- Tuberculin Purified Protein Derivative [Substance BNPC]
- Tuberculin purified protein derivative (substance) [SNOMED CT concept]
- purified protein derivative [SNOMED Notion]
- purified protein derivative of tuberculin [MeSH concept]
See also inter- (CISMeF)
- Product containing tuberculin purified protein derivative (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
concept_is_in_subset
- NICHD Terminology [NCIt concept]
- Pediatric Infectious Disease Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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