NCIt related terms : Oral Contraceptive, Combination;
NCIt definition : An oral preparation combination containing the semisynthetic estrogen ethinyl estradiol
and the synthetic progestagen norgestimate with contraceptive activity. Ethinyl estradiol
and norgestimate act by negative feed back mechanism at pituitary gland suppressing
the release of gonadotropin hormones follicle stimulating hormone (FSH) and luteinizing
hormone (LH). This combination inhibits ovulation and promotes the thickening of the
cervical mucus and the endometrium. The combination of ethinyl estradiol and norgestimate
may also be used in the treatment of acne.;