NCIt definition : A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA,
RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates
that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically
as a urinary anti-infective agent against most gram-positive and gram-negative organisms
and for long-term suppression of infections. (NCI04);