Mirtazapine - CISMeF

Preferred Label : Mirtazapine;

NCIt related terms : Remeron;

NCIt definition : A synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity. Although its mechanism of action is unknown, mirtazapine enhances central adrenergic and serotonergic transmission, possibly by acting as an antagonist at central presynaptic alpha 2 adrenergic inhibitory autoreceptors and heteroreceptors. This agent is a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors.;

Alternative definition : NCI-GLOSS: A drug used to treat depression. It belongs to the family of drugs called antidepressant agents.;

UNII : A051Q2099Q;

InChIKey : RONZAEMNMFQXRA-UHFFFAOYSA-N;

CAS number : 61337-67-5; 85650-52-8;

Drug name : Remeron;

Chemical formula : C17H19N3;

ChEBI ID : CHEBI:6950;

Codes from synonyms : CDR0000450112; CDR0000457960;

Details

Origin ID

C29265;

UMLS CUI

C0049506;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Mirtazapine [MeSH Descriptor]
- Mirtazapine [ICD-11 Extension code]
- Mirtazapine [LOINC component]
- Mirtazapine (substance) [SNOMED CT concept]
- Product containing mirtazapine (medicinal product) [SNOMED CT concept]
- mirtazapine [ATC Code]
- mirtazapine [Substance BNPC]
- mirtazapine [MeSH concept]
Validated automatic mappings to BTNT
- mirtazapine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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