Monoclonal Antibody RG 83852

Preferred Label : Monoclonal Antibody RG 83852;

NCIt synonyms : MOAB RG 83852;

NCIt definition : A murine monoclonal antibody directed against the human epidermal growth factor receptor (EGFR). Monoclonal antibody RG 83852 binds to the EGFR, inhibiting the high-affinity binding of epidermal growth factor (EGF) and receptor activation. Overexpression of EGFR, a tyrosine kinase, and its upregulated activity have been implicated in the pathogeneses of several malignancies. (NCI04);

Details

Origin ID

C29229;

UMLS CUI

C1513461;

Currated CISMeF NLP mapping
- RG 83852 monoclonal antibody [MeSH concept]
- RG 83852 monoclonal antibody [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RG 83852 monoclonal antibody [MeSH Supplementary Concept]
- RG 83852 monoclonal antibody [MeSH concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
has_target
- Epidermal Growth Factor Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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